Ultralow-dose CT urography shows
promising results
Protocol
clearly images upper urinary
tract and urolithiasis, with low
radiation dosage
By: C. P.
Kaiser
The need to
deliver as little radiation as
possible to patients was evident
during a scientific session on
CT imaging of the urinary tract.
Researchers presented studies
that ranged in dose from 20 mAs
to 200 mAs.
Dr. Ulrike G. Mueller-Lisse
and colleagues from the
University of Munich posited
that CT urography as an add-on
to contrast-enhanced CT of the
abdomen and pelvis may replace
excretory urography in patients
with pelvic tumors. But
radiation exposure is a concern,
so the researchers
retrospectively compared upper
urinary tract delineation in
low-dose and routine CT
urography.
Fourteen patients (116 upper
urinary tract segments) received
routine CT urography (120 kVp,
pitch 0.875, 175 mAs), while 26
patients (344 upper urinary
tract segments) received the
low-dose protocol (29 mAs, other
parameters unchanged). The
scanner was a four-slice
machine.
Delineation of the upper
urinary tract was equally good
for all segments in routine and
low-dose CT urography, said
coauthor Dr. Eva M. Coppenrath.
The intrarenal collecting system
and upper and middle ureter were
clearly delineated as often on
both protocols. Image quality of
the lower ureter suffered with
low-dose CT, however.
Coppenrath concluded that
low-dose CT urography was
sufficient to determine the
course of the upper urinary
tract and perhaps locate
obstruction and dilation, but it
would have been unlikely to
locate intraluminal lower ureter
lesions.
Dr. Eike Hein and colleagues
from Charite Hospital in Berlin
found that an ultralow-dose CT
protocol-with a radiation dose
comparable to a conventional
abdominal survey (KUB)-can
reliably detect urolithiasis.
Researchers in the Berlin
study prospectively examined 104
patients suspected of having
renal colic. Sixteen-slice CT
parameters included 120 kVp, 20
mAs, and pitch 23. All patients
also received an ultrasound.
The mean effective whole-body
dose of the CT scan was 0.5 mSv
in men and 0.7 mSv in women.
These values are fairly
equivalent to the dose of KUB
(0.5 to 0.9 mSv), Hein said. The
incidence of renal calculi
detected by CT was 69% in all
cases, 78% in the presence of
hematuria, and 54% without
hematuria. All renal calculi
identified by ultrasound were
detected on CT.
"Significantly more ureteral
calculi were identified on CT
than on ultrasound, whereas
there was no significant
difference in the diagnosis of
renal calculi or urinary tract
dilatation," Hein said.
The overall sensitivity for
low-dose CT was 97% compared
with 63% for ultrasound. Coronal
views are suitable for quickly
determining the size and
location of calculi, she said.
Radiologists' subjective
diagnostic confidence in
interpreting the ultralow-dose
CT scans was 80% for detecting
calculi and 91% for diagnosing
of urinary tract dilatation.