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Tumor Ablation

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WJSO | Download References | Use of a novel coaxial guide needle-wire (GNW) combination system for computed tomography guided radiofrequency tumor ablation
www.wjso.com - 10/13/11
Molecular Cancer | Email to a friend | Estrogen receptor alpha deletion enhances the metastatic phenotype of Ron overexpressing mammary tumors in mice
www.molecular-cancer.com - 1/6/12
American Journal of Gastroenterology - Erratum: Abstracts Submitted for the 76th Annual Scientific Meeting of the American College of Gastroenterology
www.nature.com - 1/1/12
Oncogene - Abstract of article: Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens
www.nature.com - 12/19/11

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Diagnostic Imaging.
 

Waste not, want not: Getting the most from imaging procedures

By Greg Freiherr | March 19, 2010

The amount of data obtained in a single MR or CT scan is mind-boggling. At least some of the data radiologists throw away could save patients money while reducing their exposure to radiation and risk of complications from invasive procedures.

“The same CT or MR scans that have been performed for other indications can be used to measure epicardial fat volume,” Dr. Paolo Raggi told me. “That is why this is such an easy piece of information to obtain.”

Easy—and possibly life-saving. Raggi, a radiologist and the director of the Emory Cardiac Imaging Center in Atlanta, has uncovered evidence that myocardial ischemia correlates more closely with epicardial adipose tissue volume than with coronary calcium score. The larger the volume of this fat that surrounds the heart, the more likely the patient has ischemia.

“This information may be used as a gatekeeper, in that it could help a cardiologist decide whether a patient should go on to have a nuclear stress test,” he said.

And that’s not all. Raggi and colleagues at Emory have discovered an association between the size of this layer of fat and the prevalence of the most dangerous type of coronary plaques, noncalcified plaques.

“Release of inflammatory factors from epicardial adipose tissue may be promoting an active atherosclerotic process, and this is indicated by the presence of noncalcified plaques,” he said.

The size of this epicardial layer of fat can be gauged from cardiac CT scans as well as MR images, according to Raggi.

While they’re at it, radiologists might keep an eye out for plaques on abdominal CTs. The presence of such plaque is a strong predictor of coronary artery disease and mortality, according to a study conducted at Henry Ford Hospital in Detroit.

“Our study clearly demonstrates that higher scores of abdominal aortic calcium are associated with higher rates of coronary artery disease and mortality,” said Dr. Mouaz Al-Mallah, director of Cardiac Imaging Research at Henry Ford.

Patients are at nearly 60% greater risk of having coronary artery disease when CTs show very high levels of abdominal aortic calcium-containing plaque. High levels of the abdominal aortic calcium also increase the risk of dying, Al-Mallah said. Conversely, researchers found that the lack of abdominal aortic calcium is associated with a low risk of coronary artery disease.

That this readily available information should be considered in assessing patients takes on added significance in the context of a Duke University study showing that cardiac catheterization finds no significant coronary artery disease in nearly 60% of chest pain patients with no history of heart disease sent for this procedure.

“We’re spending a lot of energy and money to evaluate chest pain that often leads to cardiac catheterization, which, we now know, often finds that patients don’t have significant obstructive disease,” said Dr. Manesh Patel, a cardiologist at the Duke Heart Center. “Our research shows that our methods for identifying patients at risk for obstructive disease need significant improvement.”

More than 10 million people in the U.S. experience chest pain each year. Many undergo cardiac cath to determine if blocked arteries are the culprit. This expensive test exposes the patient to substantial radiation and carries a significant risk of complications.

Patel says the entire decision-making process of caring for patients with chest pain needs to be reevaluated. Physicians need to look at everything from how patients’ histories are taken to how risk factors are assessed and the role of diagnostic testing.

A good start would be to look at how to make the best use of information already in hand. If this kind of data conservation can be proven of value in cardiac assessments, its use in other conditions will surely follow.

 

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News

WJSO | Download References | Use of a novel coaxial guide needle-wire (GNW) combination system for computed tomography guided radiofrequency tumor ablation
www.wjso.com - 10/13/11
Molecular Cancer | Email to a friend | Estrogen receptor alpha deletion enhances the metastatic phenotype of Ron overexpressing mammary tumors in mice
www.molecular-cancer.com - 1/6/12
American Journal of Gastroenterology - Erratum: Abstracts Submitted for the 76th Annual Scientific Meeting of the American College of Gastroenterology
www.nature.com - 1/1/12
Oncogene - Abstract of article: Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens
www.nature.com - 12/19/11
JNI | Full text | Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice
www.jneuroinflammation.com - 12/10/11

VoicesinRadiologyBlog


So, Imaging Technologist, You Want to Be Considered a Medical Professional
David Rushing, RT(R), MR , February 10, 2012

Over the years imaging technologists have struggled to gain a reputable identity in the healthcare field. When it comes to the hierarchy of the medical community, technologists have not fully earned the respect they deserve.

Fabricate Findings for a Payable Diagnosis?
Eric Postal, MD , February 6, 2012

In our bizarre world of getting paid not for what we do but rather why we did it, we often find ourselves holding the bag when a referrer ordered a study that the insurer decided was “inappropriate.”

Screening Ultrasound Exams Should Not Be Limited
Tim Myers, MD , February 2, 2012

The more advanced and more complicated the disease process, the more likely the patient will end up with surgery and/or amputation, increasing the cost of initial care and the additional intervention.

Radiology Comic: Doctors Cheating
James Chang, MD , January 31, 2012

 

James Chang, MD's latest comic takes on the recent news investigation into radiologists' use of recalls for board exam prep.

How to Brand Your Radiology Practice
Richard Woodcock, MD , January 30, 2012

In an environment where competition is increasing, branding your practice can be very useful. Here's how.


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'What They Should Really Teach in Medical School'
Julie Schopps, MD , February 6, 2012
The North Carolina-based pediatrician weighs in on why she thinks the real learning doesn't take place until students are out of the classroom.
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Daniel Essin, MA, MD, February 6, 2012
Separating billing-related data from other clinical documentation and transmitting it to a billing system is not difficult …no matter how the charting is done.
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I would urge each and every one of you to be familiar with the warning signs of abuse, and the resources available to you all as healthcare providers.
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