Breast images performed outside cancer centers may be interpreted differently if reinterpreted at a cancer center.
Second opinions of breast images obtained outside of cancer centers often result in a change in interpretation and treatment, according to a study published in the American Journal of Roentgenology. Researchers from Weill Cornell Medical Center and Memorial Sloan Kettering Cancer Center, in New York City, NY, performed a review to determine whether reinterpretation of studies obtained at institutions outside a cancer center influences clinical management, specifically by revealing additional cancer and preventing unnecessary biopsy. The researchers reviewed breast imaging studies of 200 patients who underwent ultrasound and MRI at community facilities and had the images submitted for second opinions at a cancer center between January and April 2014. The cases were evaluated for concordance between the original report and the second-opinion interpretation. Second-opinion review resulting in the recommendation and performance of new biopsies was further subdivided into benign, high-risk, and malignant categories based on the histopathologic results obtained at the cancer center. The results showed there was a change in interpretation in 55 of the 200 cases (28 percent) and overall, 26 recommendations (13 percent) led to a major change in management: • 20 new biopsies were performed, yielding 10 malignancies and four high-risk lesions; • Surgical management was changed to mastectomy for six of 10 patients with new sites of biopsy-proven malignancy; and• Eight biopsies were averted on the basis of benign interpretation of the imaging findings, and no disease was found at one-year follow-up evaluation. The researchers concluded reinterpretation of studies obtained outside a cancer center resulted in a change in interpretation in more than one-fourth of submitted studies. Cancer detection also was affected, with additional cancers found in 5 percent of patients and biopsy averted in 4 percent.
Stay at the forefront of radiology with the Diagnostic Imaging newsletter, delivering the latest news, clinical insights, and imaging advancements for today’s radiologists.
The Reading Room Podcast: Current and Emerging Insights on Abbreviated Breast MRI, Part 3
August 5th 2025In the last of a three-part podcast episode, Stamatia Destounis, MD, Emily Conant, MD and Habib Rahbar, MD, share additional insights on practical considerations and potential challenges in integrating abbreviated breast MRI into clinical practice, and offer their thoughts on future research directions.
The Reading Room Podcast: A Closer Look at Remote MRI Safety, Part 3
August 5th 2025In the third of a three-part podcast episode, Emanuel Kanal, M.D. and Tobias Gilk, MRSO, MRSE, discuss strategies for maintaining the integrity of time-out procedures and communication with remote MRI scanning.
Reducing the Interval Breast Cancer Rate of Screening DBT: Can AI Have an Impact?
August 5th 2025In a retrospective review of screening digital breast tomosynthesis (DBT) exams for over 200 women with interval breast cancers, researchers found that AI provided accurate localization of cancers in 32.6 percent of the cases.