• AI
  • Molecular Imaging
  • CT
  • X-Ray
  • Ultrasound
  • MRI
  • Facility Management
  • Mammography

Dynamic 4D CT provides precise measurements for aneurysm repair


Advanced imaging techniques are expanding the scope of investigation of patients undergoing stenting for an acute aortic aneurysm.

Advanced imaging techniques are expanding the scope of investigation of patients undergoing stenting for an acute aortic aneurysm.

Dynamic 4D CT is giving interventional radiologists critical information about sporadic and therefore difficult-to-detect graft-related endoleaks that may be causing an aneurysm sac to enlarge after endovascular repair.

Dynamic CT work from the University of Utrecht in the Netherlands shows that there is a 10% variation in the diameter of the thoracic aorta as blood passes through the circulation. This variation corresponds to changes of up to 3 mm in diameter during the cardiac cycle.

"You can imagine this would lead to intermittent endoleaks during the cardiac cycle in aneurysms that we treated. There are similar changes at the aortic neck in renal aneurysms, where we get up to 15% diameter changes before and after endovascular repair," said Dr. Richard G. McWilliams of the Royal Liverpool Hospital in the U.K. at the 2007 annual meeting of the Cardiovascular and Interventional Radiology Society of Europe.

Computerized modeling of CT data may greatly simplify the planning and sizing of fenestrated stent grafts to fit a specific aortic aneurysm, said Dr. Roy Greenberg, director of endovascular research at The Cleveland Clinic. Fenestrations are scallops at the top and openings of the graft that allow secure implantation, especially for cases involving a proximal neck of an aneurysm that is unsuitable for standard percutaneous endovascular repair.

At The Cleveland Clinic, a computer program uses CT scans to create a mathematical model that reconstructs and calculates the intersections of the aortic surface to provide what amounts to a mechanical drawing that will allow interventional radiologists to select an appropriately sized fenestrated device.

"With a fenestrated graft, we start with axial imaging, but axial imaging can't tell us the whole story. In today's world, you may have complex reconstructions and algorithms that give all sorts of distances. But the fundamental question you're asking is, Where is this aorta healthy?", Greenberg said.

A computer program that selects the branch vessels will allow interventional radiologists to take planning and sizing of grafts to the next level, he said.

Imaging is a particularly difficult when an aneurysm sac appears to be enlarging after endovascular repair, because it must not only carefully calculate sac diameters to confirm that there indeed has been an increase in size. Imaging must also attempt to determine whether the cause of the enlargement is endoleak, migration, attachment site dilatation, or movement at the modular connections.

An increase of 5 mm in sac diameter is the generally agreed-upon threshold for considering an aneurysm to have enlarged after endovascular repair. Aneurysm measurements can vary greatly, however, depending on when and how the sac is evaluated. The first CT after endovascular repair, rather than pretreatment scans, should be taken as the baseline measurement. Findings on pretreatment scans may be misleading because they were done weeks or even months before interventional repair, according to McWilliams.

The same axis should be chosen for each evaluation. An aneurysm may appear to be enlarging only because interpreters have chosen a different axis during follow-up. In one example, the same aneurysm could be measured at 7.1, 8, or 8.3 mm, depending on the axis, he said.

Patients who have an aneurysm sac that may be increasing in size typically undrego a combination of ultrasound, radiograph, and CT studies. An arterial phase CT is routine for follow-up, but complex cases may require triple-pass CT or translumbar sac pressure measurement.

Microleaks associated with leakage from suture holes, alterations in polyester weave, or erosion where graft fabric abducts the edges of stent components may be manifested by small jets of color on Doppler ultrasound or small areas of enhancement adjacent to the graft on CT. These leaks may be detected by injecting by hand the distal lumen occlusion, McWilliams said.

An often-forgotten area in aneurysm surveillance is the iliac zone, McWilliams said. In one case, a stent was not positioned perfectly at the bifurcation because the native iliac artery was running posteriorly, but the interventionalist had not tilted the stent caudally to the orientation of the common iliac artery and therefore missed the proper location by 3 or 4 cm.

"If you don't engage the iliac and get a good overlap zone, then as the limb starts to dilate, you get contraction into the sac with rupture in some cases," he said.

For more from the Diagnostic Imaging archives:

Cardiac CTA helps in pre- and postoperative setting

Endovascular aortic aneurysm repair provides appropriate treatment for high-risk patients

Thoracic aortic stenting outperforms surgery

Ultrasound outperforms CTA in endoleak classification

Related Videos
Does Initial CCTA Provide the Best Assessment of Stable Chest Pain?
Making the Case for Intravascular Ultrasound Use in Peripheral Vascular Interventions
Can Diffusion Microstructural Imaging Provide Insights into Long Covid Beyond Conventional MRI?
Assessing the Impact of Radiology Workforce Shortages in Rural Communities
Emerging MRI and PET Research Reveals Link Between Visceral Abdominal Fat and Early Signs of Alzheimer’s Disease
Reimbursement Challenges in Radiology: An Interview with Richard Heller, MD
Nina Kottler, MD, MS
The Executive Order on AI: Promising Development for Radiology or ‘HIPAA for AI’?
Related Content
© 2024 MJH Life Sciences

All rights reserved.