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Epix pursues breast uses for MS-325
Epix Medical of Cambridge, MA, has started phase II clinical trials for breast indications of its MS-325 MRI contrast agent. Epix and marketing partner Mallinckrodt of St. Louis are already investigating MR angiography uses for MS-325, which illuminates
Epix Medical of Cambridge, MA, has started phase II clinical trials for breast indications of its MS-325 MRI contrast agent. Epix and marketing partner Mallinckrodt of St. Louis are already investigating MR angiography uses for MS-325, which illuminates blood vessels on an MRI scan. The companies believe that the agent could also be useful for breast cancer detection, due to the increased vascularity of breast tumors. The phase II trial will test the safety and feasibility of MS-325 for detecting and characterizing benign and malignant breast lesions. MS-325 is in phase II clinical trials for peripheral vascular and carotid MRA, and is in a phase II feasibility trial for coronary MRA, according to Epix president Michael Webb.
MRI-Based AI Radiomics Model Offers 'Robust' Prediction of Perineural Invasion in Prostate Cancer
July 26th 2024A model that combines MRI-based deep learning radiomics and clinical factors demonstrated an 84.8 percent ROC AUC and a 92.6 percent precision-recall AUC for predicting perineural invasion in prostate cancer cases.
Breast MRI Study Examines Common Factors with False Negatives and False Positives
July 24th 2024The absence of ipsilateral breast hypervascularity is three times more likely to be associated with false-negative findings on breast MRI and non-mass enhancement lesions have a 4.5-fold likelihood of being linked to false-positive results, according to new research.
Can Polyenergetic Reconstruction Help Resolve Streak Artifacts in Photon Counting CT?
July 22nd 2024New research looking at photon-counting computed tomography (PCCT) demonstrated significantly reduced variation and tracheal air density attenuation with polyenergetic reconstruction in contrast to monoenergetic reconstruction on chest CT.
