fMRI scans show that babies’ brain activity can be influenced through associative learning, presenting a potential strategy for promoting the development of life-long skills in infants who have injured brains.
Advanced MRI imaging – in combination with robotics – offers a look into the activity inside a baby’s brain, opening the door to the possibility of rehabilitating babies who have brain injuries.
In a new study published in Cerebral Cortex, investigators from King’s College London visualized how brain activity can be changed through associations. These findings could have implications on promoting the development of speech, language, and movement, they said.
“A baby’s brain is constantly learning associations and changing its activity all the time so that it can respond to the new experiences that are around it,” said Tomoki Arichi, Ph.D., clinician scientist and clinical senior lecturer in the Centre for the Developing Brain. “In terms of influencing patients and interpreting it in a wider context, what it means is that we should be thinking about how we could help with disorders of brain development from a very early stage in life because we know that experience is constantly shaping the newborn brain’s activity.”
For more coverage based on industry expert insights and research, subscribe to the Diagnostic Imaging e-Newsletter here.
This study, he said, is the first to show that it is possible to alter a baby’s brain activity through associative learning with different types of sensory experiences, particularly sound.
“We…found that when a baby is learning, it actually is activating lots of different parts of the brain, so it is starting to incorporate the ‘wider network’ inside the brain which is important for processing activity,” Arichi explained.
To assess brain activity in babies, the team played the sound of a jingling bell for six seconds for 24 infants. They paired the sound with the gentle movement prompted by a custom-made 3D printed robot that they strapped to each baby’s right hand. Throughout the experiment, investigators used a functional MRI to measure brain activity.
At the end of 20 minutes of repeating the association between the sound and the movement, the team played the sound alone and compared the babies’ brain activity to that captured during the learning period. The results, Arichi said, not only shed light on what happened inside a normal baby brain, but it can also help guide clinicians who are working with infants who have injured brains.
For example, he said, if a baby cannot process movement or movement is not associated with normal activity inside his or her brain, such as in the case of cerebral palsy, clinicians could try using the association with sound to help induce learning, potentially amplifying or rehabilitating their movements.
“With our findings, it raises the possibility of trying to do something to help with that through targeted stimulation and learning associations,” Arichi said. “It is possible to induce activity inside the part of the brain that normally processes movement, for instance, just by using a single sound. This could be used in conjunction with rehabilitation or to try to help guide brain development early in life.”
Stay at the forefront of radiology with the Diagnostic Imaging newsletter, delivering the latest news, clinical insights, and imaging advancements for today’s radiologists.
Large Medicare Study Shows Black Men Less Likely to Receive PET and MRI for Prostate Cancer Imaging
August 2nd 2025An analysis of over 749,000 Medicare beneficiaries diagnosed with prostate cancer over a five-year period found that Black men were 13 percent less likely to receive PET imaging and 16 percent less likely to receive MRI in comparison to White men.
The Reading Room Podcast: Current and Emerging Insights on Abbreviated Breast MRI, Part 3
August 2nd 2025In the last of a three-part podcast episode, Stamatia Destounis, MD, Emily Conant, MD and Habib Rahbar, MD, share additional insights on practical considerations and potential challenges in integrating abbreviated breast MRI into clinical practice, and offer their thoughts on future research directions.
The Reading Room Podcast: A Closer Look at Remote MRI Safety, Part 3
August 2nd 2025In the third of a three-part podcast episode, Emanuel Kanal, M.D. and Tobias Gilk, MRSO, MRSE, discuss strategies for maintaining the integrity of time-out procedures and communication with remote MRI scanning.
Study Reveals Significant Prevalence of Abnormal PET/MRI and Dual-Energy CT Findings with Long Covid
August 2nd 2025In a prospective study involving nearly 100 patients with Long Covid, 57 percent of patients had PET/MRI abnormalities and 90 percent of the cohort had abnormalities on dual-energy CT scans.