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Molecular imaging scientist shares Nobel Prize for Chemistry
Roger Tsien, Ph.D., addressed the media Oct. 8 after learning he would share the 2008 Nobel Prize for Chemistry with Osamu Shimomura, Ph.D., and Martin Chalfie, Ph.D., for the discovery and application of green fluorescent protein as a tagging tool in bioscience and molecular imaging.
Roger Tsien, Ph.D., addressed the media Oct. 8 after learning he would share the 2008 Nobel Prize for Chemistry with Osamu Shimomura, Ph.D., and Martin Chalfie, Ph.D., for the discovery and application of green fluorescent protein as a tagging tool in bioscience and molecular imaging. Shimomura isolated the protein from a jellyfish in 1961 as a researcher at Princeton University. Chalfie demonstrated at Columbia University that the fluorescing protein could tag intracellular material in a roundworm.
At the University of California, San Diego, Tsien engineered a series of mutations creating a palette of fluorescing molecular dyes (right) that have revolutionized small animal optical imaging and molecular pharmaceutical research. (Provided by UCSD)
MRI-Based AI Radiomics Model Offers 'Robust' Prediction of Perineural Invasion in Prostate Cancer
July 26th 2024A model that combines MRI-based deep learning radiomics and clinical factors demonstrated an 84.8 percent ROC AUC and a 92.6 percent precision-recall AUC for predicting perineural invasion in prostate cancer cases.
Breast MRI Study Examines Common Factors with False Negatives and False Positives
July 24th 2024The absence of ipsilateral breast hypervascularity is three times more likely to be associated with false-negative findings on breast MRI and non-mass enhancement lesions have a 4.5-fold likelihood of being linked to false-positive results, according to new research.
Can Polyenergetic Reconstruction Help Resolve Streak Artifacts in Photon Counting CT?
July 22nd 2024New research looking at photon-counting computed tomography (PCCT) demonstrated significantly reduced variation and tracheal air density attenuation with polyenergetic reconstruction in contrast to monoenergetic reconstruction on chest CT.
