Using MRI to image the left ventricle shows more precise measurements of the heart.
The left ventricle of the heart ages differently between men and women, according to a new study published in Radiology.
Researchers from Maryland, Washington, California, North Carolina, Massachusetts, and New York sought to evaluate age-related left ventricular (LV) remodeling among both men and women who did not have clinical cardiovascular disease at the start of the study.
A total of 2,935 subjects who did not have clinical cardiovascular disease, aged 54 to 94, enrolled in the study. Slightly more than half (53%) were women. All subjects underwent baseline MRI and median time between baseline and follow-up cardiac MR imaging was 9.4 years.
Results showed that the LV mass increased in men and decreased slightly in women during the study (8.0 and 21.6 g per decade, respectively).
“The change in LV mass was positively associated with systolic blood pressure and body mass index and negatively associated with treated hypertension and high-density lipoprotein cholesterol level,” the authors wrote. The longitudinal LV mass increase was in contrast to a cross-sectional pattern of LV mass decrease.
“The shape of the heart changes over time in both men and women, but the patterns of change are different,” lead author John Eng, MD, from Johns Hopkins University School of Medicine said in a release. “Men’s hearts tend to get heavier and the amount of blood they hold is less, while women’s hearts don’t get heavier.”[[{"type":"media","view_mode":"media_crop","fid":"43059","attributes":{"alt":"John Eng, MD","class":"media-image media-image-right","id":"media_crop_7074979972057","media_crop_h":"0","media_crop_image_style":"-1","media_crop_instance":"4688","media_crop_rotate":"0","media_crop_scale_h":"0","media_crop_scale_w":"0","media_crop_w":"0","media_crop_x":"0","media_crop_y":"0","style":"float: right;","title":"John Eng, MD","typeof":"foaf:Image"}}]]
Eng pointed out that this study shows advantages offered by MRI to image the LV over other examinations. “Most heart imaging is done by echocardiography, but the measurements require a few assumptions and may not be as precise as you would like,” Eng said. “MRI gives you clearer pictures of the heart, allowing more precise computerized measurements.”
Multinational Study Reaffirms Value of Adjunctive AI for Prostate MRI
June 16th 2025The use of adjunctive AI in biparametric prostate MRI exams led to 3.3 percent and 3.4 percent increases in the AUC and specificity, respectively, for clinically significant prostate cancer (csPCa) in a 360-person cohort drawn from 53 facilities.
Study: AI-Generated ADC Maps from MRI More Than Double Specificity in Prostate Cancer Detection
June 5th 2025Emerging research showed that AI-generated ADC mapping from MRI led to significant increases in accuracy, PPV and specificity in comparison to conventional ADC mapping while achieving a 93 percent sensitivity for PCa.
Possible Real-Time Adaptive Approach to Breast MRI Suggests ‘New Era’ of AI-Directed MRI
June 3rd 2025Assessing the simulated use of AI-generated suspicion scores for determining whether one should continue with full MRI or shift to an abbreviated MRI, the authors of a new study noted comparable sensitivity, specificity, and positive predictive value for biopsies between the MRI approaches.
Can Abbreviated MRI Have an Impact in Differentiating Intraductal Papilloma and Ductal Secretion?
June 3rd 2025For patients with inconclusive ultrasound results, abbreviated breast MRI offers comparable detection of intraductal papilloma as a full breast MRI protocol at significantly reduced times for scan acquisition and interpretation, according to a new study.