PET finds early coronary disease in diabetic patients

September 8, 2008

PET may be diagnostically more powerful than ultrasound or CT for identifying early coronary artery disease in patients with type 2 diabetes.

PET may be diagnostically more powerful than ultrasound or CT for identifying early coronary artery disease in patients with type 2 diabetes.

Nuclear cardiologist Dr. Thomas Schindler and colleagues at the University of Geneva in Switzerland and the University of California, Los Angeles measured coronary endothelium dysfunction with nitrogen-13 ammonia PET and rest-stress PET.

They found diabetes patients with normal or elevated blood pressure showed significantly stronger signs of vascular disease than did normal controls. They also compared PET with high-resolution vascular ultrasound and multislice CT coronary calcium tests and found PET more sensitive than either sonography or CT. Results were presented at the 2008 SNM meeting.