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PET/CT, new radiotracers aid lung cancer diagnosis
Quantitative data and new radiotracers developed for PET/CT boost detection of lung cancer while reducing false positives, according to research presented at the RSNA meeting.
Quantitative data and new radiotracers developed for PET/CT boost detection of lung cancer while reducing false positives, according to research presented at the RSNA meeting.
Dr. Kiyoshi Nishikawa and colleagues from the Miyazaki and Tsukuba universities in Japan assessed 93 patients with PET/CT. They measured average Hounsfield units and standardized uptake units in the region of interest around pulmonary abnormalities.
The team found the combined anatomic/functional quantitative assessments were clinically useful to detect malignancies, even if these lesions are missed or misinterpreted by the PET component.
Jamey Weichert, Ph.D., and colleagues from the University of Wisconsin, Madison unveiled preliminary results with the new SPECT ligand iodine-131-labeled NM404 on six patients with advanced non-small cell lung cancer. They found patients tolerated NM404 well. They observed similar tumor uptake and retention properties in human NSCLC as previously seen in mice undergoing imaging with this agent. Studies are under way to extend NM404's utility to PET.
MRI-Based AI Radiomics Model Offers 'Robust' Prediction of Perineural Invasion in Prostate Cancer
July 26th 2024A model that combines MRI-based deep learning radiomics and clinical factors demonstrated an 84.8 percent ROC AUC and a 92.6 percent precision-recall AUC for predicting perineural invasion in prostate cancer cases.
Breast MRI Study Examines Common Factors with False Negatives and False Positives
July 24th 2024The absence of ipsilateral breast hypervascularity is three times more likely to be associated with false-negative findings on breast MRI and non-mass enhancement lesions have a 4.5-fold likelihood of being linked to false-positive results, according to new research.
Can Polyenergetic Reconstruction Help Resolve Streak Artifacts in Photon Counting CT?
July 22nd 2024New research looking at photon-counting computed tomography (PCCT) demonstrated significantly reduced variation and tracheal air density attenuation with polyenergetic reconstruction in contrast to monoenergetic reconstruction on chest CT.
