PET/CT, new radiotracers aid lung cancer diagnosis

Article

Quantitative data and new radiotracers developed for PET/CT boost detection of lung cancer while reducing false positives, according to research presented at the RSNA meeting.

Quantitative data and new radiotracers developed for PET/CT boost detection of lung cancer while reducing false positives, according to research presented at the RSNA meeting.

Dr. Kiyoshi Nishikawa and colleagues from the Miyazaki and Tsukuba universities in Japan assessed 93 patients with PET/CT. They measured average Hounsfield units and standardized uptake units in the region of interest around pulmonary abnormalities.

The team found the combined anatomic/functional quantitative assessments were clinically useful to detect malignancies, even if these lesions are missed or misinterpreted by the PET component.

Jamey Weichert, Ph.D., and colleagues from the University of Wisconsin, Madison unveiled preliminary results with the new SPECT ligand iodine-131-labeled NM404 on six patients with advanced non-small cell lung cancer. They found patients tolerated NM404 well. They observed similar tumor uptake and retention properties in human NSCLC as previously seen in mice undergoing imaging with this agent. Studies are under way to extend NM404's utility to PET.

Recent Videos
Improving Access to Nuclear Imaging: An Interview with SNMMI President Jean-Luc C. Urbain, MD, PhD
SNMMI: 18F-Piflufolastat PSMA PET/CT Offers High PPV for Local PCa Recurrence Regardless of PSA Level
SNMMI: NIH Researcher Discusses Potential of 18F-Fluciclovine for Multiple Myeloma Detection
SNMMI: What Tau PET Findings May Reveal About Modifiable Factors for Alzheimer’s Disease
Emerging Insights on the Use of FES PET for Women with Lobular Breast Cancer
Can Generative AI Reinvent Radiology Reporting?: An Interview with Samir Abboud, MD
Mammography Study Reveals Over Sixfold Higher Risk of Advanced Cancer Presentation with Symptom-Detected Cancers
Combining Advances in Computed Tomography Angiography with AI to Enhance Preventive Care
Study: MRI-Based AI Enhances Detection of Seminal Vesicle Invasion in Prostate Cancer
What New Research Reveals About the Impact of AI and DBT Screening: An Interview with Manisha Bahl, MD
Related Content
© 2025 MJH Life Sciences

All rights reserved.