Screening mammograms for women in their 40s may result in earlier high-risk breast cancer diagnosis, less chemotherapy, and lower future risk of subsequent breast cancer.
Women in their 40s who are found to have breast cancer through screening mammograms generally benefit from earlier diagnosis and may be less likely to need chemotherapy, according to a study published in the American Journal of Roentgenology.
Researchers from University Hospitals Case Medical Center, MetroHealth Medical Center, and Case Western Reserve University in Cleveland, Ohio, sought to determine if there were significant differences in how women, aged 40 to 49, were treated for high-risk lesions discovered by screening mammography compared with women with symptoms, who underwent diagnostic evaluations.
Researchers reviewed pathology results of all image-guided biopsies performed at three breast center locations from January 1, 2008, to December 31, 2011. Presentation, pathology, tumor size, stage, receptor characteristics, and treatment, were recorded for patients diagnosed with high-risk lesion or breast cancer.
Of a total of 230 primary breast cancers, the findings showed 149 cases (65 percent) were detected in the screened group and 81 (35 percent) in the non-screened group. The women in the non-screened group were more likely to undergo chemotherapy than the women in the screened group. The women in the screened group were more likely to be diagnosed at earlier stages, to have negative axillary lymph nodes, and to have smaller tumors.
The researchers concluded that because women in this age group who underwent screening mammographies found the tumors or breast cancer at their earlier stages, there was less need for chemotherapy.
“The majority of high-risk lesions were diagnosed in the screened group, which may lead to the benefit of chemoprevention, lowering their risk of subsequent breast cancer, or screening with MRI, which may diagnose future mammographically occult malignancies,” they wrote.
European Society of Breast Imaging Issues Updated Breast Cancer Screening Recommendations
April 24th 2024One of the recommendations from the European Society of Breast Imaging (EUSOBI) is annual breast MRI exams starting at 25 years of age for women deemed to be at high risk for breast cancer.
New Research Examines Socioeconomic Factors with Mammography No-Shows
April 10th 2024Patients with Medicaid or means-tested insurance were over 27 percent more likely to miss mammography appointments, and only 65 percent of women with three of more adverse social determinants of health had a mammography exam in a two-year period covering 2020 and 2021, according to new research and a report from the CDC.
Mammography Study: AI Improves Breast Cancer Detection and Reduces Reading Time with DBT
April 3rd 2024An emerging artificial intelligence (AI) model demonstrated more than 12 percent higher specificity and reduced image reading time by nearly six seconds in comparison to unassisted radiologist interpretation of digital breast tomosynthesis (DBT) images.