Just when the medical community is becoming excited about PET for Alzheimer's disease, along comes a new nemesis, the scratch-and-sniff test. Apparently, in Alzheimer's, the nose knows.
Just when the medical community is becoming excited about PET for Alzheimer's disease, along comes a new nemesis, the scratch-and-sniff test. Apparently, in Alzheimer's, the nose knows.
Autopsy results have indicated that the nerve pathways involved in smell are affected at an early stage in the brains of Alzheimer's pa-tients. Researchers at Columbia University have pinpointed 10 specific odors that patients with early Alzheimer's cannot identify: clove, leather, lemon, lilac, menthol, natural gas, pineapple, smoke, soap, and strawberry. The inability to identify these specific odors predicted who would go on to develop AD, according to Dr. Davangere Devanand and colleagues, who presented the findings at the American Col-lege of Neuropsychopharmacology meeting in December.
Devanand had ear-lier found a global relationship between loss of smell and Alzheimer's. But knowing the specific odors involved can help physicians make a definitive diagnosis and start therapy earlier, he said.
Considering Breast- and Lesion-Level Assessments with Mammography AI: What New Research Reveals
June 27th 2025While there was a decline of AUC for mammography AI software from breast-level assessments to lesion-level evaluation, the authors of a new study, involving 1,200 women, found that AI offered over a seven percent higher AUC for lesion-level interpretation in comparison to unassisted expert readers.