Adding one-view tomosynthesis to digital mammography improves diagnostic accuracy and reduces recall rates, but adding two-view tomosynthesis provides even better results.
Adding two-view tomosynthesis to conventional digital mammography (DM) improves diagnostic accuracy and reduces the recall rate even more than does one-view tomosynthesis, according to a study published in the American Journal of Roentgenology.
Researchers from Massachusetts General Hospital in Boston compared two methods of combining tomosynthesis with digital mammography by assessing diagnostic accuracy and recall rates for digital mammography alone and digital mammography combined with one-view tomosynthesis and two-view tomosynthesis.
A total of 310 cases were included in the study, including 51 biopsy-proven malignancies, 47 biopsy-proven benign findings, 138 recalled screening cases, and 74 negative screening cases. Fifteen radiologists reviewed the cases sequentially using digital mammography, and adding one-view tomosynthesis, and then two-view tomosynthesis.
After the cases were assessed for recall, each was assigned a BI-RADS score and probability of malignancy for each imaging method. Diagnostic accuracy was assessed using receiver operating characteristic (ROC) analysis. Screening recall rates were compared using pooled logistical regression analysis.
The researchers found that the average noncancer recall rate for DM was 44.2 percent; for DM plus one-view tomosynthesis, 27.2 percent; and for DM plus two-view tomosynthesis, 24.0 percent. Both one-view and two-view tomosynthesis combined with DM showed significantly lower noncancer recall rates than DM alone, the researchers noted. In addition, the two-view tomosynthesis was had a significantly lower recall rate than the one-view tomosynthesis.
Diagnostic accuracy for nondense breasts improved with DM plus two-view tomosynthesis compared with digital mammography alone. Compared with digital mammography, diagnostic sensitivity for invasive cancers increased with the addition of both one-view and two- tomosynthesis.
The researchers concluded that adding one-view tomosynthesis to conventional DM improved both diagnostic accuracy and recall rate, but adding two-view tomosynthesis provided twice the performance gain in diagnostic accuracy while further reducing the recall rate.
Contrast-Enhanced Mammography and Dense Breasts: What a New Meta-Analysis Reveals
May 1st 2024The 10-study meta-analysis demonstrated that contrast-enhanced mammography has a 95 percent sensitivity rate and an 81 percent specificity rate for diagnosing suspicious lesions in women with dense breasts.
European Society of Breast Imaging Issues Updated Breast Cancer Screening Recommendations
April 24th 2024One of the recommendations from the European Society of Breast Imaging (EUSOBI) is annual breast MRI exams starting at 25 years of age for women deemed to be at high risk for breast cancer.
New Research Examines Socioeconomic Factors with Mammography No-Shows
April 10th 2024Patients with Medicaid or means-tested insurance were over 27 percent more likely to miss mammography appointments, and only 65 percent of women with three of more adverse social determinants of health had a mammography exam in a two-year period covering 2020 and 2021, according to new research and a report from the CDC.
Mammography-Based AI Abnormality Scoring May Improve Prediction of Invasive Upgrade of DCIS
April 9th 2024Emerging research suggests that an artificial intelligence (AI) score of 75 or greater for mammography abnormalities more than doubles the likelihood of invasive upgrade of ductal carcinoma in situ (DCIS) diagnosed with percutaneous biopsy.