June 3rd 2006
Successful radiological research requires correlation with a gold standard that is accepted as the best diagnostic test or optimum method for treatment assessment. This may involve analysis of a pathologic specimen or another invasive procedure. Such standards are, however, associated with long observation times or a need for surgical exploration. Using the five-year survival rate, a relatively long time in the setting of a cancer therapy, would prevent many patients from benefiting from a potentially successful treatment option.