• AI
  • Molecular Imaging
  • CT
  • X-Ray
  • Ultrasound
  • MRI
  • Facility Management
  • Mammography

3D MR brings new insight into bipolar disorders

Article

Three-D MR is lending new muscle to the theory that lithium rebuilds or repairs gray matter in specific regions of the brain in patients with bipolar disorders.

Three-D MR is lending new muscle to the theory that lithium rebuilds or repairs gray matter in specific regions of the brain in patients with bipolar disorders.

Principal investigator Carrie Bearden, Ph.D., and colleagues at the University of California, Los Angeles enrolled 28 adult patients with bipolar disorder, most of whom were being treated with lithium, and 28 healthy subjects. The investigators used 3D structural brain mapping to analyze gray matter spots at multiple cortical locations. They found a statistically significant difference in gray matter density between bipolar patients and control subjects in the brain regions that control attention, motivation, and emotion. The technique will help develop new treatments that match lithium's effectiveness but without its toxic effects, Bearden said.

Investigators published results in the July issue of Biological Psychiatry.

Recent Videos
Emerging Research at SNMMI Examines 18F-flotufolastat in Managing Primary and Recurrent Prostate Cancer
Could Pluvicto Have a Role in Taxane-Naïve mCRPC?: An Interview with Oliver Sartor, MD
New SNMMI President Cathy Cutler, PhD, Discusses Current Challenges and Goals for Nuclear Medicine
Where the USPSTF Breast Cancer Screening Recommendations Fall Short: An Interview with Stacy Smith-Foley, MD
A Closer Look at MRI-Guided Transurethral Ultrasound Ablation for Intermediate Risk Prostate Cancer
Improving the Quality of Breast MRI Acquisition and Processing
Can Fiber Optic RealShape (FORS) Technology Provide a Viable Alternative to X-Rays for Aortic Procedures?
Does Initial CCTA Provide the Best Assessment of Stable Chest Pain?
Making the Case for Intravascular Ultrasound Use in Peripheral Vascular Interventions
Can Diffusion Microstructural Imaging Provide Insights into Long Covid Beyond Conventional MRI?
Related Content
© 2024 MJH Life Sciences

All rights reserved.