NeoRx has become the latest monoclonal antibody developer to benefitfrom the Food and Drug Administration's increased attention towardMoAb products. The Seattle company announced last week that theFDA has issued final approval for Verluma, a small-cell
NeoRx has become the latest monoclonal antibody developer to benefitfrom the Food and Drug Administration's increased attention towardMoAb products. The Seattle company announced last week that theFDA has issued final approval for Verluma, a small-cell lung cancerimaging agent (SCAN 12/27/95).
The FDA's action triggered a $4.5 million milestone paymentto NeoRx from Du Pont Merck Pharmaceutical, the product's NorthAmerican licensee. Boehringer Ingelheim affiliate Dr. Karl ThomaeGmbH is licensed to manufacture Verluma. The agent was formerlyknown as OncoTrac.
Verluma is composed of a monoclonal antibody Fab fragment linkedto a technetium-99m tracer. Verluma is indicated to determinethe stage of disease in a small-cell lung cancer patient, whichcan affect the course of therapy.
NeoRx is developing a cancer therapy agent, Avicidin, whichuses a different formulation of the Verluma antibody to home inon cancer sites. Avicidin is in phase I/II clinical trials.
Stay at the forefront of radiology with the Diagnostic Imaging newsletter, delivering the latest news, clinical insights, and imaging advancements for today’s radiologists.
Study Shows Enhanced Diagnosis of Coronary Artery Stenosis with Photon-Counting CTA
July 10th 2025In a new study comparing standard resolution and ultra-high resolution modes for patients undergoing coronary CTA with photon-counting detector CT, researchers found that segment-level sensitivity and accuracy rates for diagnosing coronary artery stenosis were consistently > 89.6 percent.
FDA Expands Approval of MRI-Guided Ultrasound Treatment for Patients with Parkinson’s Disease
July 9th 2025For patients with advanced Parkinson’s disease, the expanded FDA approval of the Exablate Neuro platform allows for the use of MRI-guided focused ultrasound in performing staged bilateral pallidothalamic tractotomy.