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PET, SPECT surpass clinical tests for AD
How well a patient counts, remembers word lists, or performs other basic tests may not indicate how far Alzheimer's dementia has progressed biologically, according to a study presented at the RSNA meeting.
How well a patient counts, remembers word lists, or performs other basic tests may not indicate how far Alzheimer's dementia has progressed biologically, according to a study presented at the RSNA meeting.
The Mini-Mental Status Exam has been the standard diagnostic tool for Alzheimer's disease for years, relying on a series of simple cognitive tests to calculate a score for degree of mental impairment. In 58 patients who also underwent PET or SPECT imaging, however, the MMSE showed little correlation with imaging evidence of advanced disease.
Many patients with near-normal MMSE scores showed pronounced bilateral defects on imaging, while others with extremely low MMSE scores showed only moderate PET or SPECT perfusion defects, according to Amitha Rao, a third-year medical student at the University of Kansas, who completed the research under the direction of radiologist Dr. Reginald Dusing.
MRI-Based AI Radiomics Model Offers 'Robust' Prediction of Perineural Invasion in Prostate Cancer
July 26th 2024A model that combines MRI-based deep learning radiomics and clinical factors demonstrated an 84.8 percent ROC AUC and a 92.6 percent precision-recall AUC for predicting perineural invasion in prostate cancer cases.
Breast MRI Study Examines Common Factors with False Negatives and False Positives
July 24th 2024The absence of ipsilateral breast hypervascularity is three times more likely to be associated with false-negative findings on breast MRI and non-mass enhancement lesions have a 4.5-fold likelihood of being linked to false-positive results, according to new research.
Can Polyenergetic Reconstruction Help Resolve Streak Artifacts in Photon Counting CT?
July 22nd 2024New research looking at photon-counting computed tomography (PCCT) demonstrated significantly reduced variation and tracheal air density attenuation with polyenergetic reconstruction in contrast to monoenergetic reconstruction on chest CT.
