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PET tops CT for malignant lung nodule characterization
A large multicenter trial rates FDG-PET as more reliable than CT for the detection of malignant solitary pulmonary nodules. Findings suggest, however, that a combined, rather than single, modality approach may lead to earlier treatment and help avoid invasive procedures.
A large multicenter trial rates FDG-PET as more reliable than CT for the detection of malignant solitary pulmonary nodules. Findings suggest, however, that a combined, rather than single, modality approach may lead to earlier treatment and help avoid invasive procedures.
From January 1999 to June 2001, lead investigator Dr. James W. Fletcher and colleagues at 10 VA hospitals in seven states prospectively enrolled 344 patients with a recent SPN diagnosis who had not yet been treated for the condition. All patients underwent FDG-PET and CT scanning. Researchers correlated imaging results with biopsies from 184 of these patients and two-year follow-up data from 160 of them. The investigators found that PET results interpreted as definitely malignant were 10 times more likely to be true positives than CT's. However, both PET and CT could predict benign diagnoses. They published results in the Journal of Nuclear Medicine (2008;49:179-185).
MRI-Based AI Radiomics Model Offers 'Robust' Prediction of Perineural Invasion in Prostate Cancer
July 26th 2024A model that combines MRI-based deep learning radiomics and clinical factors demonstrated an 84.8 percent ROC AUC and a 92.6 percent precision-recall AUC for predicting perineural invasion in prostate cancer cases.
Breast MRI Study Examines Common Factors with False Negatives and False Positives
July 24th 2024The absence of ipsilateral breast hypervascularity is three times more likely to be associated with false-negative findings on breast MRI and non-mass enhancement lesions have a 4.5-fold likelihood of being linked to false-positive results, according to new research.
Can Polyenergetic Reconstruction Help Resolve Streak Artifacts in Photon Counting CT?
July 22nd 2024New research looking at photon-counting computed tomography (PCCT) demonstrated significantly reduced variation and tracheal air density attenuation with polyenergetic reconstruction in contrast to monoenergetic reconstruction on chest CT.
