Multislice CT angiography boasts multiple advantages over MRA and digital subtraction angiography for detecting cerebral aneurysms, but the playing field is changing. Advances in rotational DSA (rDSA) are turning that technique into a powerful tool, said Dr. Nancy Fischbein, a neuroradiologist at Stanford University, speaking at the seventh annual Symposium on Multidetector-Row CT in San Francisco.
Multislice CT angiography boasts multiple advantages over MRA and digital subtraction angiography for detecting cerebral aneurysms, but the playing field is changing. Advances in rotational DSA (rDSA) are turning that technique into a powerful tool, said Dr. Nancy Fischbein, a neuroradiologist at Stanford University, speaking at the seventh annual Symposium on Multidetector-Row CT in San Francisco.
Key advantages of CT include speed and ease of use, high resolution, and the ability to visualize veins and adjacent anatomy and to demonstrate active bleeding. Where CT weakens compared with MRA and DSA is its dependence on radiation, iodinated contrast, bolus injection, and complex postprocessing.
MRA also offers high resolution, albeit lower than CTA. But postprocessing, repeat exams, and follow-up are all easily performed. MRA drawbacks in cerebral aneurysm detection include contraindications, inability to scan very sick or uncooperative patients, and flow and susceptibility artifacts, Fischbein said.
DSA is the accepted gold standard, with high resolution and a rotational option. But its invasive nature and complications rate are significant drawbacks.
For screening to determine if an aneurysm is present, both CTA and MRA are useful, according to Fischbein. In diagnostic mode, to address acute symptoms or suspected subarachnoid hemorrhage, CTA is preferred. DSA is the winning technique for use in treatment.
For initial evaluation and diagnosis, however, the question remains whether both CTA and DSA are needed, she said.
"CTA can guide and limit the DSA exam, providing a road map for surgeons if patients cannot complete angiography," she said. "Many patients are simply unable to hold still long enough."
Use of CTA alone is an increasingly viable option, but all three techniques are constantly evolving, Fischbein said. A review of the literature shows that rDSA is more accurate than CTA in aneurysm detection, but the findings have not been statistically significant.
CTA advances in progress will overcome limitations related to skull base evaluations and postprocessing methods. But one of its biggest pitfalls - when radiologists miss multiple aneurysms because they stop looking after finding one - can be avoided simply by paying better attention, she said.
"I call it the rule of 'n-plus-one'," Fischbein said. "Where there is one aneurysm there might be more. Keep looking. Don't assume you've satisfied your search just because you've found one or even two cerebral aneurysms."
Stay at the forefront of radiology with the Diagnostic Imaging newsletter, delivering the latest news, clinical insights, and imaging advancements for today’s radiologists.
Study Shows Enhanced Diagnosis of Coronary Artery Stenosis with Photon-Counting CTA
July 10th 2025In a new study comparing standard resolution and ultra-high resolution modes for patients undergoing coronary CTA with photon-counting detector CT, researchers found that segment-level sensitivity and accuracy rates for diagnosing coronary artery stenosis were consistently > 89.6 percent.
FDA Expands Approval of MRI-Guided Ultrasound Treatment for Patients with Parkinson’s Disease
July 9th 2025For patients with advanced Parkinson’s disease, the expanded FDA approval of the Exablate Neuro platform allows for the use of MRI-guided focused ultrasound in performing staged bilateral pallidothalamic tractotomy.