SIR: Renal Denervation Helps Control Hypertension
HealthDay News - Approach found to reduce resistant hypertension when current medications fail
HealthDay News - Renal denervation (RDN) appears to be safe and effective in reducing and controlling hypertension among individuals with uncontrolled hypertension when current medications fail, according to research presented at the annual meeting of the Society of Interventional Radiology, held from March 26 to 31 in Chicago.
Marc R. Sapoval, MD, PhD, of the Hôpital Européen Georges-Pompidou in Paris, and colleagues randomized 106 patients with uncontrolled hypertension, despite receiving at least three antihypertensive medications, to RDN or oral treatment (control).
After six months of follow-up, the investigators found that systolic pressure fell an average of 32 mm Hg and diastolic pressure fell an average of 12 mm Hg among those who underwent RDN. The investigators are currently expanding the initial cohort to a multicenter randomized controlled trial at 24 international sites. The researchers note that endovascular RDN may also have applicability in disease states such as heart failure, cardio-renal syndrome, hepato-renal syndrome, insulin resistance-metabolic syndrome, and the prevention of progression of chronic kidney disease and hypertension in end-stage renal disease.
"Renal denervation, a minimally invasive, effective treatment, appears to be safe in the short term with a low incidence of local complications. Its efficacy to lower blood pressure in patients with resistant high blood pressure will be better evaluated with the results of a subsequent trial," Sapoval said in a statement. "After six months, 39 percent of patients receiving the endovascular denervation treatment had reached the recommended blood pressure level and, overall, 50 percent of patients showed a measurable benefit of the intervention."
The study was funded by the catheter and specific generator manufacturer.
Copyright © 2011 HealthDay. All rights reserved.
Clarius Mobile Health Unveils Anterior Knee Feature for Handheld Ultrasound
April 23rd 2025The T-Mode Anterior Knee feature reportedly offers a combination of automated segmentation and real-time conversion of grayscale ultrasound images into color-coded visuals that bolster understanding for novice ultrasound users.
The Reading Room Podcast: Current Perspectives on the Updated Appropriate Use Criteria for Brain PET
March 18th 2025In a new podcast, Satoshi Minoshima, M.D., Ph.D., and James Williams, Ph.D., share their insights on the recently updated appropriate use criteria for amyloid PET and tau PET in patients with mild cognitive impairment.
What is the Best Use of AI in CT Lung Cancer Screening?
April 18th 2025In comparison to radiologist assessment, the use of AI to pre-screen patients with low-dose CT lung cancer screening provided a 12 percent reduction in mean interpretation time with a slight increase in specificity and a slight decrease in the recall rate, according to new research.
