Sonus completes phase-one trials

Article

Ultrasound contrast agent developerSonus Pharmaceuticals announced this month that its EchoGen agenthas completed phase-one clinical trials. Sonus, of Bothell, WA,made the announcement at the Alex. Brown & Sons Medical Conferencein Baltimore.

Ultrasound contrast agent developerSonus Pharmaceuticals announced this month that its EchoGen agenthas completed phase-one clinical trials. Sonus, of Bothell, WA,made the announcement at the Alex. Brown & Sons Medical Conferencein Baltimore.

EchoGen is the first agent in the Sonus pipeline. It is basedon an emulsion that turns into echogenic microbubbles when injected(SCAN 1/19/94).

The phase-one trial involved administration of EchoGen to 25healthy male subjects and obtaining blood samples to measure drugcontent and to detect potential safety parameters over a 72-hourperiod.

EchoGen appeared safe under the conditions of the study andthe drug was cleared from the body quickly after images were obtained,according to Sonus president and CEO Dr. Steven C. Quay.

In addition, EchoGen provided diagnostically useful informationabout heart, kidney and liver function and the vascular systemin 88% of the subjects in the study. Sonus will use the resultsof the study to develop phase-two clinical trials for EchoGenin cardiology and radiology, as well as an exercise-stress echocardiologystudy for myocardial perfusion.

Recent Videos
Study: MRI-Based AI Enhances Detection of Seminal Vesicle Invasion in Prostate Cancer
What New Research Reveals About the Impact of AI and DBT Screening: An Interview with Manisha Bahl, MD
Can AI Assessment of Longitudinal MRI Scans Improve Prediction for Pediatric Glioma Recurrence?
A Closer Look at MRI-Guided Adaptive Radiotherapy for Monitoring and Treating Glioblastomas
Incorporating CT Colonography into Radiology Practice
What New Research Reveals About Computed Tomography and Radiation-Induced Cancer Risk
What New Interventional Radiology Research Reveals About Treatment for Breast Cancer Liver Metastases
New Mammography Studies Assess Image-Based AI Risk Models and Breast Arterial Calcification Detection
Can Deep Learning Provide a CT-Less Alternative for Attenuation Compensation with SPECT MPI?
Employing AI in Detecting Subdural Hematomas on Head CTs: An Interview with Jeremy Heit, MD, PhD
Related Content
© 2025 MJH Life Sciences

All rights reserved.