Researchers can for the first time visualize coronary artery plaques vulnerable to rupture using spectral CT, an innovation that will lead to better and earlier diagnosis of cardiovascular disease, according to researchers.
Researchers can for the first time visualize coronary artery plaques vulnerable to rupture using spectral CT, an innovation that will lead to better and earlier diagnosis of cardiovascular disease, according to researchers.
Ruptured atherosclerotic plaques are the cause of nearly 70% of heart attacks. High-density lipoproteins (HDL) gravitate to plaques vulnerable to rupture and remove them from the arterial wall. Researchers from Mount Sinai in New York inserted tiny gold particles into HDL and injected mice with them. Using a spectral CT scanner from Philips Medical Systems, the researchers were able to see the gold particles as the HDL targeted microphages, thus illuminating the location of the vulnerable plaques.
Conventional CT doesn’t provide enough contrast to differentiate types and density of tissue. Spectral CT shows the effect of gold particles while also distinguishing calcium deposits and contrast agents. Together, this information is used to identify stenoses, thus helping define both the severity of atherosclerosis and heart attack risk.
ASCO: Study Reveals Significant Racial/Ethnic Disparities with PSMA PET Use for Patients with mPCa
May 30th 2025Latinx patients with metastatic prostate cancer were 63 percent less likely than non-Hispanic White patients to have PSMA PET scans, according to a study of 550 patients presented at the American Society of Clinical Oncology (ASCO) conference.
Lunit Unveils Enhanced AI-Powered CXR Software Update
May 28th 2025The Lunit Insight CXR4 update reportedly offers new features such as current-prior comparison of chest X-rays (CXRs), acute bone fracture detection and a 99.5 percent negative predictive value (NPV) for identifying normal CXRs.
New MRI Study Questions Use of Corticosteroid Injections for Knee OA
May 27th 2025Two years after intraarticular knee injections for knee osteoarthritis (OA), study participants who had corticosteroid knee injections had greater OA progression than control patients while the use of hyaluronic acid injections was associated with less OA progression.