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Three-D PET tracks response to lung cancer therapy
Patients with mesothelioma, a cancer of the lung lining caused by exposure to asbestos, may someday benefit from a new 3D PET measure that helps accurately and quickly measure response to chemotherapy, according to Australian researchers.
Patients with mesothelioma, a cancer of the lung lining caused by exposure to asbestos, may someday benefit from a new 3D PET measure that helps accurately and quickly measure response to chemotherapy, according to Australian researchers.
Investigators at Sir Charles Gairdner Hospital's PET Center in Western Australia and other area centers developed software to assess total glycolytic volume (TGV), a 3D measure that reflects tumor volume and metabolic activity on FDG-PET scans. They compared TGV and maximum standardized uptake values (SUVmax) for PET and CT-based measures on 23 patients with mesothelioma set to undergo cisplatin and gemcitabine treatment.
Results showed that TGV can measure tumor response after just one round of chemotherapy. TGV also proved more accurate predicting survival than did both SUVmax and CT (JNM 2007:48:1449-1458).
MRI-Based AI Radiomics Model Offers 'Robust' Prediction of Perineural Invasion in Prostate Cancer
July 26th 2024A model that combines MRI-based deep learning radiomics and clinical factors demonstrated an 84.8 percent ROC AUC and a 92.6 percent precision-recall AUC for predicting perineural invasion in prostate cancer cases.
Breast MRI Study Examines Common Factors with False Negatives and False Positives
July 24th 2024The absence of ipsilateral breast hypervascularity is three times more likely to be associated with false-negative findings on breast MRI and non-mass enhancement lesions have a 4.5-fold likelihood of being linked to false-positive results, according to new research.
Can Polyenergetic Reconstruction Help Resolve Streak Artifacts in Photon Counting CT?
July 22nd 2024New research looking at photon-counting computed tomography (PCCT) demonstrated significantly reduced variation and tracheal air density attenuation with polyenergetic reconstruction in contrast to monoenergetic reconstruction on chest CT.
