New Study Shows Viability of Adjunctive AI for Breast Ultrasound

In new research comparing the use of adjunctive artificial intelligence (AI) to radiologist assessment of breast ultrasound images, researchers found that adjunctive AI had over a 28 percent higher accuracy rate and a nearly 40 percent higher specificity rate for diagnosing breast lesions.

For the retrospective study, presented at the recent Society of Breast Imaging (SBI) conference, researchers assessed the adjunctive use of Koios Decision Support (DS) Breast (Koios Medical) in interpreting breast ultrasound for the diagnosis of breast lesions. The study involved 154 biopsy-proven cases (mean age of 53.2) from a diverse patient population comprised of 33.1 percent White patients, 29.9 percent Hispanic patients, 15.6 percent Black/African American patients, 14 percent Asian patients and 12.3 percent multi-racial patients, according to the study.

The researchers found that use of the Koios DS Breast software had a 60.4 accuracy rate in comparison to a 31.8 percent accuracy rate for radiologist assessment of breast lesions on ultrasound as well as a 97.5 sensitivity rate. There was also a significant reduction of false positives with the AI software (60) in comparison to 105 false positive diagnoses for radiologist assessment without AI.

“Our preliminary results show there is promise that an AI (decision support) system would be an accurate and reliable second opinion in diagnostic ultrasound examinations,” noted lead study author Clara Koo, M.D., a diagnostic radiology resident affiliated with the Mount Sinai Health System in New York, N.Y., and colleagues. “Furthermore, (the AI software) has the potential to reduce false positive readings, especially in younger patients, reducing the burden of unnecessary biopsies.”

In the diverse patient cohort, the researchers also noted no evidence of racial- or machine-based bias affecting the study results. Koo and colleagues added that there was increasing correlation between the AI software and radiologist assessment with advancing patient age.

(Editor’s note: For related content, see “Automated Breast Ultrasound: Is it a Viable Second-Look Option for Women with Dense Breasts?” and “Can Multimodal AI Improve Cancer Detection in Dense Breasts?”)