Diagnostic Imaging Vol 31 No 2

Studies examining the clinical historiesof patients who developednephrogenic systemic fibrosis aftertreatment at distinguished teachinghospitals in New York City andVienna suggest that gadoliniumbasedcontrast dose and post-MRIhemodialysis are keys to controllingthe rare but deadly skin disorder

I read with interest your article on nephrogenic systemic fibrosis and the “heavy collateraldamage” that radiologists face due to the off-label uses of gadoliniumagents and subsequent development of NSF in somepatients

Researchers were stunned when preliminary results of an ongoing study showed that patients who undergo vertebroplasty may die sooner than patients with vertebral fractures who do not undergo the procedure.

Despite encouraging earlier results, themuch-awaited follow-up phase III DIAS-2trial on ischemic stroke patients treated withdesmoteplase afterthe onset of symptomsdid not showany improvement inclinical response at90 days.

An incidental finding of multiple sclerosistypelesions during brain MRI is no fluke. Anew study has found that some patientsdevelop the physical symptoms of the diseasewithin five years of the abnormalities'discovery on MRI.