DuPont Pharmaceuticals reported this month that it has submitted a new drug application (NDA) to the Food and Drug Administration for Definity, an ultrasound contrast agent formerly known as DMP 115, MRX 115, and Aerosomes. North Billerica, MA-based Du
DuPont Pharmaceuticals reported this month that it has submitted a new drug application (NDA) to the Food and Drug Administration for Definity, an ultrasound contrast agent formerly known as DMP 115, MRX 115, and Aerosomes. North Billerica, MA-based Du Pont hopes Definity will be the first multiuse contrast agent, with applications for both echocardiography and abdominal ultrasound.
For cardiac ultrasound, Definity would enhance ultrasound imaging of cardiac structure and functioning. For abdominal ultrasound, the agent would improve imaging of the liver and kidney. DuPont based its NDA on seven multicenter U.S. clinical trials, which included more than 600 patients.
MRI-Based AI Radiomics Model Offers 'Robust' Prediction of Perineural Invasion in Prostate Cancer
July 26th 2024A model that combines MRI-based deep learning radiomics and clinical factors demonstrated an 84.8 percent ROC AUC and a 92.6 percent precision-recall AUC for predicting perineural invasion in prostate cancer cases.
Breast MRI Study Examines Common Factors with False Negatives and False Positives
July 24th 2024The absence of ipsilateral breast hypervascularity is three times more likely to be associated with false-negative findings on breast MRI and non-mass enhancement lesions have a 4.5-fold likelihood of being linked to false-positive results, according to new research.
Can Polyenergetic Reconstruction Help Resolve Streak Artifacts in Photon Counting CT?
July 22nd 2024New research looking at photon-counting computed tomography (PCCT) demonstrated significantly reduced variation and tracheal air density attenuation with polyenergetic reconstruction in contrast to monoenergetic reconstruction on chest CT.