fMRI predicts benign brain tumors that turn malignant

Article

Perfusion-weighted MRI can anticipate the transformation of low-grade gliomas into malignant tumors up to a year earlier than other imaging tests, according to researchers. The technique could help select patients who may benefit from more aggressive treatment.

Perfusion-weighted MRI can anticipate the transformation of low-grade gliomas into malignant tumors up to a year earlier than other imaging tests, according to researchers. The technique could help select patients who may benefit from more aggressive treatment.

Adam Waldman, Ph.D., and colleagues at the Charing Cross Hospital in London prospectively enrolled 13 patients with low-grade gliomas for two years ending in August 2002. Patients underwent perfusion- and contrast-enhanced MRI every six months for up to three years to check for tumor malignancy. Investigators found that increases in blood volume by perfusion MRI suggested malignancy a year or more before it could be observed by contrast MR. They published their findings in the April issue of Radiology.

Newsletter

Stay at the forefront of radiology with the Diagnostic Imaging newsletter, delivering the latest news, clinical insights, and imaging advancements for today’s radiologists.

Recent Videos
SNMMI: Emerging PET Insights on Neuroinflammation with Progressive Apraxia of Speech (PAOS) and Parkinson-Plus Syndrome
Improving Access to Nuclear Imaging: An Interview with SNMMI President Jean-Luc C. Urbain, MD, PhD
SNMMI: 18F-Piflufolastat PSMA PET/CT Offers High PPV for Local PCa Recurrence Regardless of PSA Level
SNMMI: NIH Researcher Discusses Potential of 18F-Fluciclovine for Multiple Myeloma Detection
SNMMI: What Tau PET Findings May Reveal About Modifiable Factors for Alzheimer’s Disease
Emerging Insights on the Use of FES PET for Women with Lobular Breast Cancer
Can Generative AI Reinvent Radiology Reporting?: An Interview with Samir Abboud, MD
Mammography Study Reveals Over Sixfold Higher Risk of Advanced Cancer Presentation with Symptom-Detected Cancers
Combining Advances in Computed Tomography Angiography with AI to Enhance Preventive Care
Study: MRI-Based AI Enhances Detection of Seminal Vesicle Invasion in Prostate Cancer
Related Content
© 2025 MJH Life Sciences

All rights reserved.