A molecular imaging technique may prove useful in early assessment of treatment response for cisplatin-resistant ovarian cancer, according to a study published in the Journal of Nuclear Medicine.
A molecular imaging technique may prove useful in early assessment of treatment response for cisplatin-resistant ovarian cancer, according to a study published in the Journal of Nuclear Medicine. Cisplatin is often effective against ovarian cancer when first given, but tumors can become resistant and start growing again.
The study showed F-18 fluorothymidine (F-FLT) PET was able to predict early response to everolimus (a mammalian target of rapamycin inhibitor) in cisplatin-resistant ovarian cancer in mice. The technique should be considered for therapeutic assessment in humans, according to the researchers.
No significant change in tumor F-FLT uptake was observed in the controls. In the everolimus-treated mice, F-FLT standard uptake value decreased by 33% on the second day of treatment and by 66% on the seventh day. There were also changes in tumor volume.
Can Emerging AI Software Offer Detection of CAD on CCTA on Par with Radiologists?
May 14th 2025In a study involving over 1,000 patients who had coronary computed tomography angiography (CCTA) exams, AI software demonstrated a 90 percent AUC for assessments of cases > CAD-RADS 3 and 4A and had a 98 percent NPV for obstructive coronary artery disease.
Study Examines CT-Based AI Detection of Incidental Abdominal Aortic Aneurysms
April 29th 2025The AI software Viz AAA offered a sensitivity of 87.5 percent in detecting abdominal aortic aneurysms on contrast-enhanced CT, according to new retrospective research presented at the American Roentgen Ray Society (ARRS) conference.