Autopsy studies indicate that soft plaque with a fibrous cap measuring less than 65 microns is at risk of imminent rupture. Multislice CT and MR imaging, with resolutions around 200 and 300 microns, respectively, cannot help predict a rupture. Optical coherence tomography (OCT), however, can obtain an in vivo resolution well below 65 microns.
Autopsy studies indicate that soft plaque with a fibrous cap measuring less than 65 microns is at risk of imminent rupture. Multislice CT and MR imaging, with resolutions around 200 and 300 microns, respectively, cannot help predict a rupture. Optical coherence tomography (OCT), however, can obtain an in vivo resolution well below 65 microns.
Dr. Osamu Katoh and colleagues at Toyohashi Heart Center in Japan used OCT to measure minimal and maximal thickness and length of the fibrous caps in stable and vulnerable plaques (Am J Cardiol 2004;94[suppl 6A]:142E). Four lesions were considered vulnerable, and three were considered stable.
The mean minimal thickness of the fibrous caps was significantly less in the vulnerable group (30 microns) than in the stable group (70 microns). The differences in maximal thickness and length between the two groups were not significant.
MRI-Based AI Radiomics Model Offers 'Robust' Prediction of Perineural Invasion in Prostate Cancer
July 26th 2024A model that combines MRI-based deep learning radiomics and clinical factors demonstrated an 84.8 percent ROC AUC and a 92.6 percent precision-recall AUC for predicting perineural invasion in prostate cancer cases.
Breast MRI Study Examines Common Factors with False Negatives and False Positives
July 24th 2024The absence of ipsilateral breast hypervascularity is three times more likely to be associated with false-negative findings on breast MRI and non-mass enhancement lesions have a 4.5-fold likelihood of being linked to false-positive results, according to new research.
Can Polyenergetic Reconstruction Help Resolve Streak Artifacts in Photon Counting CT?
July 22nd 2024New research looking at photon-counting computed tomography (PCCT) demonstrated significantly reduced variation and tracheal air density attenuation with polyenergetic reconstruction in contrast to monoenergetic reconstruction on chest CT.