• AI
  • Molecular Imaging
  • CT
  • X-Ray
  • Ultrasound
  • MRI
  • Facility Management
  • Mammography

MRI Not Quite There for Lymph Node Diagnosis in Breast Cancer

Article

Magnetic resonance imaging’s accuracy in detecting cancer in the lymph nodes of newly diagnosed breast cancer patients is nothing to sniff at – 80 percent with diffusion-weighted MRI and 85 percent with axial T1-weighted MRI, Canadian researchers have reported. But it’s not quite high enough to skip a lymph node dissection, according to a study published online Dec. 5 in the journal Radiology.

Magnetic resonance imaging’s accuracy in detecting cancer in the lymph nodes of newly diagnosed breast cancer patients is nothing to sniff at – 80 percent with diffusion-weighted MRI and 85 percent with axial T1-weighted MRI, Canadian researchers have reported. But it’s not quite high enough to skip a lymph node dissection, according to a study published online Dec. 5 in the journal Radiology.

University of Toronto researchers chose 61 women (average age 53) with invasive breast cancer to undergo preoperative breast MRI. Axial T1-weighted MRI without fat saturation and diffusion-weighted (DW) MR images were analyzed by two experienced radiologists uninformed of the pathology findings.

They found the sensitivity, specificity, and accuracy to be 88 percent, 82 percent, and 85 percent, respectively, for axial T1-weighted MR imaging and 84 percent, 77 percent, and 80 percent for diffusion-weighted (DW) imaging. Apparent diffusion coefficients (ADCs) were significantly lower in the malignant group.

The team concluded that unenhanced MRI techniques showed high accuracy in the preoperative evaluation of patients with invasive breast cancer, and that, while the results indicated reliable and reproducible assessment with DW imaging, “it is unlikely to be useful in clinical practice.”

Related Videos
Emerging Research at SNMMI Examines 18F-flotufolastat in Managing Primary and Recurrent Prostate Cancer
Could Pluvicto Have a Role in Taxane-Naïve mCRPC?: An Interview with Oliver Sartor, MD
New SNMMI President Cathy Cutler, PhD, Discusses Current Challenges and Goals for Nuclear Medicine
Where the USPSTF Breast Cancer Screening Recommendations Fall Short: An Interview with Stacy Smith-Foley, MD
A Closer Look at MRI-Guided Transurethral Ultrasound Ablation for Intermediate Risk Prostate Cancer
Improving the Quality of Breast MRI Acquisition and Processing
Can Fiber Optic RealShape (FORS) Technology Provide a Viable Alternative to X-Rays for Aortic Procedures?
Does Initial CCTA Provide the Best Assessment of Stable Chest Pain?
Making the Case for Intravascular Ultrasound Use in Peripheral Vascular Interventions
Can Diffusion Microstructural Imaging Provide Insights into Long Covid Beyond Conventional MRI?
Related Content
© 2024 MJH Life Sciences

All rights reserved.