Progressive Lower Limb Weakness
Case History: 56-year-old man presents with progressive weakness in lower limbs for four to five years
Case History: 56-year-old man presents with progressive weakness in lower limbs for four to five years and occasional episodes of spontaneous falling.
56-year-old man presents with progressive weakness in lower limbs for four to five years and occasional episodes of spontaneous falling.
Figure 1. MRI at the level of upper thighs: Axial T1 weighted pulse sequence shows symmetric atrophy, fatty infiltration, and edema of the bilateral quadriceps muscles (arrows)
Figure 2. Short inversion tau recovery (STIR) pulse sequence shows symmetric atrophy, fatty infiltration and edema of the bilateral quadriceps muscles (arrows).
Diagnosis: Inclusion body myositis
Inclusion body myositis (IBM) is the most common idiopathic inflammatory myopathy occurring in patients over age 50.
Typical MRI findings include bilateral and symmetrical involvement of muscles with fatty infiltration and edema.
There is no definitive cure or standard course of treatment for IBM.
