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Riverain’s Chest X-Ray Comparison Tool Gets FDA Nod


Temporal Comparison software compares current and prior chest X-rays to help identify nodules that may be early-stage lung cancer.

Riverain Technologies, a Dayton, Ohio-based medical technology company, has received FDA 510(k) clearance for its Temporal Comparison software, which compares current and prior chest X-rays and can help identify nodules that may be early-stage lung cancer, the company announced.

The technology targets differences between the X-rays, drawing attention to what could be an emerging or enlarging tumor. The software aligns the two images to produce a difference image, which the company said allows radiologists to identify subtle changes more clearly.

In a study of 422 pairs of chest X-rays, 15 radiologists demonstrated an average of 12.4 percent improvement in sensitivity for actionable solitary pulmonary nodules using the software, compared to results viewing the X-rays side by side, the company said.

The software can be used with Riverain’s Bone Suppression software, which removes the bones from the image to make differences more conspicuous.

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