Most radiologists surveyed by the Society for Radiologists in Ultrasound said they perform more than 10 thyroid aspirations each week. But few used consistent criteria to determine which nodules were chosen for aspiration. Institutions performing more thyroid aspirations seem to find more malignant nodules, but the survey didn’t determine if this was a result of better methodology or simply a matter of patient selection.
Most radiologists surveyed by the Society for Radiologists in Ultrasound said they perform more than 10 thyroid aspirations each week. But few used consistent criteria to determine which nodules were chosen for aspiration. Institutions performing more thyroid aspirations seem to find more malignant nodules, but the survey didn't determine if this was a result of better methodology or simply a matter of patient selection.
Dr. Roberta diFlorio-Alexander, a radiologist at Dartmouth-Hitchcock Medical Center in New Hampshire, presented results of the survey distributed by the SRU to its fellows at the 2006 RSNA meeting. Radiologists answered questions about volume of thyroid procedures, criteria used for choosing which thyroid nodules would be aspirated, procedural methods such as needle size preference, and incidence of cytopathology.
Roughly half of the 46 respondents said they routinely biopsied multiple thyroid nodules on each patient. Ultrasound is unable to diagnose malignancy, but certain characteristics are considered suspicious, and these criteria are used in deciding which nodules to biopsy. The size of a nodule, for instance, can be determined with ultrasound, and this is a common criterion, but size has never been shown to be an indication of cytopathology. Microcalcifications were another common criterion used, along with other sonographic features unusual for thyroid tissue.
Slightly more than half of the biopsies using these criteria found cytopathology present in slightly more than half the nodules aspirated. Twenty-five percent of the rest had nondiagnostic results. Malignancy rates in thyroid aspirates ranged between 5% and 20%.
Variations in criteria used may account for some of the variability in results. A consensus statement published by the SRU in 2005 attempted to standardize the criteria. Among the consensus panel's conclusions:
Specific recommendations appear in chart form, and the full text of the report is available.
The recommendations allow physicians some flexibility in the selection of which nodules require fine-needle aspiration. The decision to perform or defer ultrasound-guided fine-needle aspiration for a particular thyroid nodule in a given patient should be made by the physician according to the individual circumstances.
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