MR diffusion studies differentiate prostate cancer
Contrast-enhanced MR diffusion and perfusion were able to differentiate between central gland prostate cancer and benign prostate hyperplasia, according to a study published in Radiology.
Contrast-enhanced MR diffusion and perfusion were able to differentiate between central gland prostate cancer and benign prostate hyperplasia, according to a study published in Radiology.
The apparent diffusion coefficient differs significantly between central gland carcinoma, stromal hyperplasia, and glandular hyperplasia. Using ADC can help physicians distinguish between cancerous and benign tissue. In addition, combining the rate of contrast transfer between blood and tissue with the ADC can also aid the detection of central gland cancer.
In their retrospective study, the University of Chicago researchers included 49 patients who underwent endorectal MR imaging followed by radical prostatectomy, 26 of whom had central gland cancer.
The researchers found the ADC was 1.05 for central gland carcinoma, 1.27 for stromal hyperplasia foci, and 1.73 for glandular hyperplasia foci. Perfusion parameters were similar in central gland carcinomas and stromal hyperplasia foci. Adding the contrast agent transfer rate between blood and tissue to the ADC increased sensitivity from 38% to 57%. Adding the contrast agent transfer rate between blood and tissue to the ADC increased specificity to 90%.
Newsletter
Stay at the forefront of radiology with the Diagnostic Imaging newsletter, delivering the latest news, clinical insights, and imaging advancements for today’s radiologists.
The Reading Room Podcast: A Closer Look at Remote MRI Safety, Part 3
August 1st 2025In the third of a three-part podcast episode, Emanuel Kanal, M.D. and Tobias Gilk, MRSO, MRSE, discuss strategies for maintaining the integrity of time-out procedures and communication with remote MRI scanning.
The Reading Room Podcast: A Closer Look at Remote MRI Safety, Part 2
August 1st 2025In the second of a multi-part podcast episode, Emanuel Kanal, M.D. and Tobias Gilk, MRSO, MRSE, share their perspectives on remote MRI safety protocols for ensuring screening accuracy and adherence to conditional implant guidelines as well as a rapid and effective response to adverse events.
Twenty Years of CT Colonography for Colorectal Cancer Screening: What the Research Reveals
August 1st 2025Computed tomography colonography (CTC) demonstrated a 91.6 percent positive predictive value (PPV) for polyps > 6 mm, according to new research involving over 9,000 patients who underwent CTC for primary asymptomatic colorectal cancer screening.
