• AI
  • Molecular Imaging
  • CT
  • X-Ray
  • Ultrasound
  • MRI
  • Facility Management
  • Mammography

Europeans bask in glow of MR blood pool images

Article

Peripheral MR angiography (far right) is improved on first-pass imaging due to the high relaxivity of the MR blood pool agent Vasovist. The extended imaging window provided by the agent supports steady-state imaging not possible with other MR contrast media, producing ultrahigh spatial resolution MRA (second pass) demonstrating both arteries and veins in detail.

Peripheral MR angiography (far right) is improved on first-pass imaging due to the high relaxivity of the MR blood pool agent Vasovist. The extended imaging window provided by the agent supports steady-state imaging not possible with other MR contrast media, producing ultrahigh spatial resolution MRA (second pass) demonstrating both arteries and veins in detail.

The blood pool agent, highlighted on the exhibit floor of the European Congress of Radiology in March, is available in Europe but not the U.S. Reviewers at the FDA have asked its developer, Epix Pharmaceuticals, for more clinical data before making a decision. In late February, Epix appealed the request, asking that the FDA Center for Drug Evaluation and Research approve Vasovist on the merits of data already presented. This is the company's second appeal. The first, made last August to the FDA Office of Drugs, failed. The appeals go back to 2005, when the FDA issued an approvable letter regarding the agent but asked for more data.

Vasovist is now being sold in the European Union, Canada, Norway, Iceland, and Australia. Bayer Schering Pharma, which is marketing the agent outside the U.S. under a distribution agreement with Epix, is exploring the use of Vasovist in advanced applications. A leading candidate is the detection of pulmonary embolism (arrow, top left image) following deep venous thrombosis (arrow, bottom left image). (Provided by Bayer Schering Pharma)

Related Videos
Improving the Quality of Breast MRI Acquisition and Processing
Can Diffusion Microstructural Imaging Provide Insights into Long Covid Beyond Conventional MRI?
Emerging MRI and PET Research Reveals Link Between Visceral Abdominal Fat and Early Signs of Alzheimer’s Disease
Nina Kottler, MD, MS
Practical Insights on CT and MRI Neuroimaging and Reporting for Stroke Patients
Related Content
© 2024 MJH Life Sciences

All rights reserved.