Screening CT Colonography for Osteoporosis
CT colonography to screen for colorectal cancer also gives physicians the opportunity to assess patients for osteoporosis.
Analysis of CT colonography for colorectal cancer can provide information regarding patient bone health and osteoporosis, according to a study published in Radiology.
Researchers from the Mayo Clinic in Rochester, NY, and the University of California–Berkeley, in California, evaluated the utility of retrospective analysis of CT colonography in a comprehensive osteoporosis assessment.
The study involved 136 women, aged from 43 to 92, who had undergone CT colonography and DXA within a six-month period between January 2008 and April 2010. The diagnosis of osteoporosis and assessment of fracture risk were compared between biomechanical CT analysis and dual-energy X-ray absorptiometry (DXA).
“For bone mineral density T scores at the femoral neck, biomechanical CT analysis was highly correlated (R2 = 0.84) with DXA, did not differ from DXA (P = .15, paired t test), and was able to identify osteoporosis (as defined by DXA), with 100 percent sensitivity in eight of eight patients and 98.4 percent specificity in 126 of 128 patients,” the authors wrote.[[{"type":"media","view_mode":"media_crop","fid":"41062","attributes":{"alt":"musculoskeletal imaging","class":"media-image media-image-right","id":"media_crop_2405273398736","media_crop_h":"0","media_crop_image_style":"-1","media_crop_instance":"4279","media_crop_rotate":"0","media_crop_scale_h":"0","media_crop_scale_w":"0","media_crop_w":"0","media_crop_x":"0","media_crop_y":"0","style":"height: 200px; width: 200px; border-width: 0px; border-style: solid; margin: 1px; float: right;","title":"©decade3d - anatomy online/Shutterstock.com","typeof":"foaf:Image"}}]]
When the researchers looked at both the hip and spine, the classification of patients at high risk for fracture by biomechanical CT analysis corresponded with classifications for clinical osteoporosis by DXA with 82.8% sensitivity in 24 of 29 patients and 85.7% specificity in 66 of 77 patients.
The researchers concluded that without changing imaging protocols, use of CT colonography performed for colorectal cancer screening also provides a comprehensive osteoporosis assessment.
Photon-Counting Computed Tomography: Eleven Takeaways from a New Literature Review
May 27th 2025In a review of 155 studies, researchers examined the capabilities of photon-counting computed tomography (PCCT) for enhanced accuracy, tissue characterization, artifact reduction and reduced radiation dosing across thoracic, abdominal, and cardiothoracic imaging applications.
Can AI Predict Future Lung Cancer Risk from a Single CT Scan?
May 19th 2025In never-smokers, deep learning assessment of single baseline low-dose computed tomography (CT) scans demonstrated a 79 percent AUC for predicting lung cancer up to six years later, according to new research presented today at the American Thoracic Society (ATS) 2025 International Conference.
Can Emerging AI Software Offer Detection of CAD on CCTA on Par with Radiologists?
May 14th 2025In a study involving over 1,000 patients who had coronary computed tomography angiography (CCTA) exams, AI software demonstrated a 90 percent AUC for assessments of cases > CAD-RADS 3 and 4A and had a 98 percent NPV for obstructive coronary artery disease.
