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Academic radiologists usually cut to the chase in describing how imaging increasingly factors into drug discovery and research. They display cellular metabolism FDG-PET images or dynamic-contrast MR images quantifying changes in tumor vascularity. These glamor children of radiological research reflect the potential of medical imaging in measuring therapeutic response.

Myelination, the development of a protective sheath for nerve fibers, may dramatically increase when adults enter their forties before beginning to decline in old age, according to a study presented Sunday at the RSNA meeting. The finding contradicts long-held beliefs that myelination is a normal process of brain maturation that is largely complete by early adulthood.

High-field 3D MR angiography can put up a good fight against conventional x-ray digital subtraction angiography for the diagnosis of brain aneurysms and other intracranial vascular malformations, according to studies presented at the RSNA meeting Monday. Three-D MRA also provides reliable follow-up after treatment.

Myelination, the development of a protective sheath for nerve fibers, may dramatically increase when adults enter their forties before beginning to decline in old age, according to a study presented Sunday. The finding contradicts long-held beliefs that myelination is a normal process of brain maturation that is largely complete by early adulthood.

GE Healthcare played to high-field enthusiasts visiting the RSNA exhibit floor Sunday, unveiling three MR scanners – one at 3T and two at 1.5T.

An app to die for

There was a time when all that really mattered in medical imaging was technology that dealt with, well, medicine. That’s changed. Though clinical molecular imaging using advanced biomarkers is still a ways away, we’ve opened the door a crack to use miniature PET scanners in animal research with these agents. Now one of life’s inevitabilities is wedging the door open a bit more.

Whole-body MRI with a nonenhanced imaging sequence can provide accurate staging of lymphoma. Contrast agents and other improvements could take this accuracy even further, making MRI an alternative to CT and PET, according to researchers at Mater Misericordiae Hospital in Dublin.

To paraphrase Mark Twain, reports of the death of diagnostic MR spectroscopy are greatly exaggerated. CPT 76390 is considered standard of care as an effective imaging technique for the diagnosis, treatment, and monitoring of patients with brain lesions by Cigna Healthcare, a respected healthcare provider,1 though declared "investigational" by Blue Shield, Anthem, and Medicare. Radiologists and other physicians are confused and annoyed by some insurers' refusal to reimburse for their MRS services.

Discoveries relating to the imaging of hypoxia, angiogenesis, and ligand receptors demonstrate the scientific prowess of the In vivo Cellular Molecular Imaging Center at Johns Hopkins University and justify its reputation as one of the top molecular imaging laboratories in the world.

Exquisite images of the brain, spine, body, and joints will adorn vendors' booths at the RSNA meeting, attesting to the benefits of clinical 3T. But, unlike the many ultrahigh-field MR scans that vendors have displayed in the past, most of these 3T images will come from systems designed for everyday clinical practice.

Computer-aided detection is evolving from an interesting technological trapping to a standard of care. Part of that process involves the ongoing iterative advancement expected to be on display at the RSNA meeting.

Researchers from The Children’s Hospital of Philadelphia have performed real-time functional cardiac MRI in fetuses. Theirs is the first report of this technique, which may represent an advance over the current gold standard of fetal echocardiography.

Despite the image of young snowboarders recklessly bombing downhill, the popular sport actually has no greater percentage of injuries than does skiing. Snowboarders have their own types of injuries, however, related to factors unique to the sport.

Working with colleagues at the former CTI PET Systems in Knoxville, Siemens Medical Solutions engineers in Erlangen, Germany, are assembling a prototype PET/MR scanner designed to overcome technical barriers that have thus far kept a hybrid of these two modalities from clinical use.

Could patients with possible biliary and/or pancreatic disease soon be offered a piña colada before imaging? Not quite, but a team of Belgian radiologists has started serving pineapple juice labeled with gadolinium to boost the quality of its MR cholangiopancreatography scans.

In recent years, the use of MR perfusion- and diffusion-based imaging to predict tissue outcome following acute ischemic stroke has increased significantly. While most strategies to improve outcome have focused on MRI parameters, researchers from Boston and Finland have devised a novel approach that also includes spatial information.

A drainage implant or device, also known as a tube shunt, is implanted in the sclera of patients with glaucoma to maintain an artificial drainage pathway and control intraocular pressure. Intraocular pressure is lowered when aqueous humor flows from inside the eye through the tube into the space between the plate that rests on the scleral surface and surrounding fibrous capsule.(1-3)

TV cops are unlikely to visit their local MR center when extracting confessions from suspected criminals. But the appearance of 3T scanners on detective programs could simply be a matter of time, following research demonstrating the accuracy of fMRI-based lie detection.

Putting the wind back in 3T

The Gulf Coast is under attack, not from Mother Nature but from a nefarious group of evil-doers. Somehow these sneaky scoundrels have gotten their hands on an electromagnetic generator that makes hurricanes, and they are using it to pelt the U.S. with one storm after the other. That’s the theory, at least, of Scott Stevens, an Idaho TV weather forecaster.