History of Cough, Mild Weight Loss
Case History: 49-year-old patient presented with history of cough; mild weight loss was noted.
Case History: A 49-year-old patient presented with history of cough; mild weight loss was noted.
49-year-old patient presented with history of cough; mild weight loss was noted.
Figure 1. CT scanogram shows upper lobe fibrosis and multiple nodules in upper lobes.
Figure 2A. Shows confluent upper lobe fibrosis and multiple nodules in upper lobes. Some nodules appear in perilymphatic distribution.
Figure 2B. Shows confluent upper lobe fibrosis and multiple nodules in upper lobes. Some nodules appear in perilymphatic distribution.
Figure 2C. Shows confluent upper lobe fibrosis and multiple nodules in upper lobes. Some nodules appear in perilymphatic distribution.
Figure 2D. Shows confluent upper lobe fibrosis and multiple nodules in upper lobes. Some nodules appear in perilymphatic distribution.
Figure 3A. Shows enlarged lymph nodes in mediastinum and bilateral hilar regions.
Figure 3B. Shows enlarged lymph nodes in mediastinum and bilateral hilar regions.
Figure 3C. Shows enlarged lymph nodes in mediastinum and bilateral hilar regions.
Enlarged mediastinal and bilateral hilar lymph nodes were seen.
Ninety percent of patients have pulmonary involvement (although many are asymptomatic), and since chest X-rays are readily available and have low radiation burden, the pattern of nodal and parenchymal involvement is used to “stage” sarcoidosis.
Sarcoidosis is a noncaseating granulomatous multi-system disease.
Although the age of presentation is very broad, sarcoidosis most commonly affects patients between 20 and 40 years of age.
Clinical presentation is variable and diagnosis is usually made based on a combination of clinical and radiological features
The granulomas may resolve spontaneously or progress to fibrosis.
Treatment is primarily with corticosteroids, which must be used judiciously.Â
Complications are organ dependent.
