News|Articles|November 3, 2026

Is Late Arterial Phase CT Necessary for Undifferentiated Acute Abdominal Pain?

Author(s)Jeff Hall

New research found that the late arterial phase, which accounts for approximately 40 percent of CT radiation dosing in cases involving acute abdominal pain, offered no exclusive findings that had an impact on clinical care.

Could low-kV portal venous phase CT provide sufficient diagnostic yield for patients with undifferentiated acute abdominal pain?

In a retrospective study recently published in the European Journal of Radiology, researchers reviewed multiphasic low-kV CT data for 96 patients (mean age of 54) with undifferentiated abdominal pain and assessed the utility of the portal venous phase (PVP) and late arterial phase (LAP). The reviewing readers were a board-certified radiologist with sub-specialization in gastrointestinal (GI) imaging and a radiology resident with experience in GI imaging, according to the study.

Is the Portal Venous Phase Enough in CT Imaging for Acute Abdominal Pain?

The study authors found that PVP offered average sensitivity, specificity and accuracy of 91.5 percent, 81.25 percent specificity and 90.6 percent, respectively, for the detecting relevant pathologies in this patient population.

There were concordant results between the reviewing radiologist and resident in 85.4 percent of the cases, according to the researchers. They also noted no LAP-specific findings that contributed to clinical management of the patients.

“Our findings … suggest that a portal venous phase (PVP)-only protocol may be sufficient to address the relevant clinical question in patients with undifferentiated abdominal pain, while additional arterial imaging should be reserved for specific diagnostic indications,”noted lead study author Roland Cronenberg, MD, who is affiliated with the Department of Biomedical Imaging and Image-Guided Therapy at the Medical University of Vienna in Vienna, Austria, and colleagues.

Key Findings with Radiation Dosing in CT Imaging of Acute Abdominal Pain

The researchers emphasized that employing low-kV techniques can facilitate enhanced views of hypervascular and hypovascular abnormalities in parenchymal abdominal organs as well as significant reductions in CT radiation dosing.

Additionally, out of the total mean dose-length product (DLP) of 501.5 mGy*cm for the study, the mean DLP values for LAP and PVP were 204.6 mGy*cm and 296.9 mGy*cm respectively.

Three Key Takeaways

• A PVP-only protocol may be enough for most undifferentiated acute abdominal pain. Low-kV portal venous phase (PVP) imaging alone achieved average sensitivity, specificity and accuracy of 91.5 percent, 81.25 percent and 90.6 percent, respectively, for detecting relevant pathology. No late arterial phase (LAP) findings contributed to clinical management.

• Dropping routine arterial imaging can meaningfully cut radiation dose. The late arterial phase accounted for 40.8 percent of the total dose-length product (mean 204.6 of 501.5 mGy*cm). Omitting it when it adds no clinically relevant information could substantially reduce radiation exposure.

• Arterial phase imaging still has a defined role. The authors recommend keeping it for suspected active bleeding or vascular pathology and for patients older than 75.

“In our cohort, the LAP accounted for 40.8% of the total dose-length product, corresponding to a mean estimated effective dose of approximately 3.1 mSv. Therefore, avoiding routine acquisition of the LAP when it does not provide additional clinically relevant information could substantially reduce radiation exposure,” maintained Cronenberg and colleagues.

The study authors cautioned that there may be increased image noise when employing reduced tube voltage, and that this may be more pronounced in those with larger body habitus. They also emphasized the necessity of arterial imaging in cases involving suspicion of active bleeding or vascular pathology, and for patients older than 75.

(Editor’s note: For related content, see “Improving Adherence to Best Practices for Incidental Abdominal Aortic Aneurysms on CT and MRI,” “Emerging Advances in Photon-Counting Computed Tomography” and “FDA Clears AI-Powered Triage Software for 10 Findings on Abdominopelvic CT.”)

Beyond the inherent limitations of a single-center retrospective study, the authors noted the possibility of incomplete clinical information for some cases and acknowledged that patients with vascular emergencies were underrepresented in the cohort. The researchers also conceded that the cohort was drawn from a tertiary care facility, which may limit application of the study findings to broader patient populations.


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