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Liver imaging is benefiting considerably from the improvement of ultrasound systems and sequences dedicated to contrast-enhanced examinations. The use of ultrasound contrast to detect and characterize focal liver lesions is now routine.

Whole-body MRI is more sensitive but less specific than FDG-PET/CT for cancer detection, according to researchers from China and Europe. Findings suggest a complementary rather than exclusive role in oncologic imaging for both modalities and validate recent studies suggesting close follow-up since either test can miss metastases.

The controversial topic of nephrogenic systemic fibrosis featured prominently in this year’s European Congress of Radiology program. This scleroderma-like disorder has been linked to the administration of gadolinium-containing contrast media. Despite the growing wealth of data on incidence of the disorder, however, researchers remain unable to pin down the causal trigger.

An epileptic seizure is the external manifestation of a functional cerebral disorder that can affect 10% of the world's population. Virtually any brain abnormality can irritate vulnerable neurons and produce epileptic seizures. The nature and characteristics of the seizure depend on the part of the brain involved in the disturbance.

Perfusion-weighted MR imaging can anticipate the transformation of low-grade gliomas into malignant tumors up to a year earlier than other imaging tests, according to British researchers. MRI could help determine which patients may benefit more from aggressive treatment.

Researchers in San Francisco have found that MR imaging can accurately predict recurrence and development of metastatic disease in patients who are about to undergo radiation therapy for prostate cancer. Study findings suggest a stronger role for MRI in the management of the condition.

Hitachi executives hope their booth at the ISMRM meeting will serve as a springboard for sales of their open 1.2T Oasis, set to begin shipping this month. The new high-field scanner is the company’s chance to rekindle a market that has all but collapsed in the past several years with the advent of compact wide-bore 1.5T devices and expanding clinical applications for such high-performance systems.

Above and around the Siemens Healthcare booth at the ISMRM meeting, the message “pushing the boundaries of MR” was as clear as it could be. The theme was driven home by pennants featuring iconic reconstructions of athletes into whole-body 2D renditions of muscles and organs. How the company pushes these boundaries, however, had been more subtext than headline, an issue Siemens vice president of marketing for MR Don Fowler set out to resolve on the ISMRM exhibit floor.

New MR spectroscopy findings indicate that changes in brain glutamate levels reflect changes in heroin craving among addicts during methadone maintenance therapy. MRS may eventually help predict if addicts will relapse after treatment.

Quality Electrodynamics has constructed and tested a 32-channel cardiac array for use on the Toshiba 1.5T Vantage Atlas that its developers say will provide acceleration factors in any direction, including oblique phase-encoding, which is often applied in cardiac imaging.

A comprehensive evaluation of Magnevist use among the 3.3 million members of Kaiser Permanente in Northern California has found a lower risk for developing nephrogenic systemic fibrosis than reported in previous studies in renal disease patients who received gadolinium-based MR contrast media.

Quantitative MR, characterized by the precise measurement of data points that underlie MR images, may one day provide an exact and definable basis to recognize the early signs of disease and response to therapy. Philips Healthcare is moving toward that day, developing techniques that quantify the presence of cancerous tumors and heart disease.

GE Healthcare’s gas-based MRI imaging strategy may find a home, if tests of the technology by Merck pan out. The pharmaceutical company plans to audition GE’s Spin Signal Technology (SST) utilizing hyperpolarized xenon 129 gas for use in assessing its experimental respiratory treatments.